What's Happening?
Lifordi Immunotherapeutics, a clinical-stage biotech company, has secured a strategic investment from Sanofi Ventures and additional funding from existing investors, bringing the total raised to $112 million. The funds will support the ongoing Phase 1 study
of LFD-200, an antibody-drug conjugate (ADC) for treating autoimmune and inflammatory disorders. LFD-200 targets myeloid and lymphoid cells using a cell surface membrane protein (VISTA). The investment will also facilitate Chemistry Manufacturing and Controls (CMC) preparations for Phase 2 clinical supply. Christopher Gagliardi, Ph.D., from Sanofi Ventures, will join Lifordi's Board of Directors as an observer.
Why It's Important?
This investment underscores the growing interest in ADCs as a promising therapeutic approach for autoimmune and inflammatory disorders. Lifordi's focus on leveraging ADC technology could lead to innovative treatments that offer improved efficacy and safety profiles compared to traditional therapies. For the biotech industry, this funding highlights the importance of strategic partnerships and investments in advancing drug development. The involvement of Sanofi Ventures, a major player in the healthcare sector, adds credibility and resources to Lifordi's efforts, potentially accelerating the development and commercialization of LFD-200.
What's Next?
Lifordi will continue its Phase 1 study of LFD-200, with initial data expected in the coming months. The company will also prepare for Phase 2 clinical trials, ensuring a smooth transition and availability of clinical supply. As the development progresses, stakeholders, including investors, researchers, and patients, will be keenly interested in the trial outcomes and any potential partnerships or collaborations that may arise.












