What's Happening?
ChemDiv, a global provider of drug discovery solutions, has announced its continued support for Clywedog Therapeutics following its merger with Barinthus Therapeutics. The merger will result in the formation
of Clywedog Therapeutics, Inc., which will be listed on Nasdaq under the ticker CLYD. ChemDiv will provide chemistry, computational, and clinical pharmacology support to advance clinical-stage candidates in Type 1 and Type 2 diabetes, as well as celiac disease. The collaboration includes accelerated CMC research, AI-enabled pharmacology, and computational modeling. ChemDiv's services have been crucial in advancing MEN PPI inhibitors and TYK2 inhibitors, which show promise in treating diabetes by enhancing islet cell proliferation and reducing pro-inflammatory cytokine signaling, respectively.
Why It's Important?
This merger and continued support from ChemDiv are significant for the biopharmaceutical industry, particularly in the field of diabetes research. By combining expertise in immunology and metabolic diseases, the new entity aims to accelerate the development of innovative treatments for diabetes and celiac disease. The collaboration leverages ChemDiv's advanced drug discovery capabilities, potentially leading to faster development of effective therapies. This could have a substantial impact on patients suffering from these chronic conditions, offering new hope for improved management and treatment options. The merger also highlights the growing trend of strategic partnerships in the biopharmaceutical sector to enhance research and development capabilities.
What's Next?
The merger is expected to be finalized in the first half of 2026, with leadership comprising executives from both Barinthus and Clywedog. The combined company will focus on achieving multiple near-term data milestones for its clinical-stage assets. As the merger progresses, stakeholders will likely monitor the integration of the two companies' operations and the impact on ongoing research projects. The success of this merger could influence future collaborations and mergers in the biopharmaceutical industry, particularly those aimed at addressing complex diseases like diabetes.











