What's Happening?
A recent study presented at the American Heart Association's Scientific Sessions 2025 has found a potential link between long-term melatonin use and an increased risk of heart failure. The study analyzed health data from over 130,000 adults with insomnia
and discovered that those who took melatonin for a year or longer were more likely to develop heart failure, be hospitalized for the condition, or die from any cause compared to non-users. While the study does not establish a direct causal relationship, it raises concerns about the safety of prolonged melatonin use, a common over-the-counter sleep aid in the U.S.
Why It's Important?
The findings challenge the perception of melatonin as a safe, natural remedy for sleep issues. With millions of Americans using melatonin supplements, the potential health risks highlighted by this study could have significant public health implications. The research suggests that long-term use of melatonin may not be as harmless as previously thought, prompting healthcare providers to reconsider how they counsel patients on sleep aids. The study also underscores the need for more rigorous regulation and research into the long-term effects of dietary supplements.
What's Next?
Further research is needed to confirm these findings and explore the mechanisms by which melatonin might influence heart health. The study's results may lead to increased scrutiny of melatonin supplements and potentially influence regulatory policies. Healthcare professionals might begin advising patients to use melatonin with caution, especially for extended periods, and consider alternative treatments for insomnia.
