Landmark Deal to Make HIV Prevention Drug Lenacapavir Affordable in Low-Income Countries

What's Happening?

A landmark agreement has been reached to make the HIV prevention drug Lenacapavir available at a lower cost in over 100 low-income countries. The deal, involving the Clinton Health Access Initiative, Gates Foundation, and other groups, aims to provide affordable access to the drug, which stops the virus from replicating inside cells. Lenacapavir, administered by injection, offers six months of protection against HIV infection and is expected to transform prevention efforts, especially for underserved communities. The drug has already received backing from the World Health Organization and regulatory approval from the US FDA and European Commission.

Why It's Important?

The availability of Lenacapavir at a reduced cost is a significant step towards ending the HIV/AIDS epidemic, providing millions with access to effective prevention. Long-acting injectables like Lenacapavir could reduce new infections in vulnerable populations, including young women, LGBT people, and sex workers. The drug's affordability addresses the challenges of daily oral PrEP, which can be stigmatized and difficult to access consistently. The initiative highlights the importance of partnerships in global health, particularly amid cuts to US foreign aid programs affecting HIV/AIDS efforts.

What's Next?

The rollout of the lower-cost version of Lenacapavir is planned for 2027, with efforts to build demand and prepare systems for rapid introduction. The drug's potential to prevent up to 20% of new HIV infections underscores the need for continued collaboration with communities and governments. As the generic version awaits regulatory approval, stakeholders are focused on ensuring widespread access and addressing the ongoing challenges in global health, particularly in regions with high HIV prevalence.