What's Happening?
Researchers in Sweden have successfully extracted RNA from a 130-year-old Tasmanian tiger, marking a significant milestone in genetics research. Led by Dr. Marc R. Friedländer at Stockholm University, the team was able to identify active genes in the tissues
of the extinct marsupial, also known as a thylacine. This achievement is notable because RNA, which is crucial for understanding gene expression, typically degrades faster than DNA. The specimen, preserved in a Swedish museum, provided skin and muscle tissue for sequencing. The study utilized metatranscriptomics to differentiate thylacine RNA from potential contaminants, ensuring the accuracy of their findings. This research opens new possibilities for studying extinct species and understanding their biology through RNA analysis.
Why It's Important?
This breakthrough in retrieving RNA from an extinct species has significant implications for the field of paleogenomics. It allows scientists to study gene expression in extinct animals, providing insights into their biology and evolution. The ability to analyze RNA from preserved specimens could lead to a better understanding of extinct species' physiology and adaptation mechanisms. This research also highlights the potential for museum specimens to preserve genetic information, which could be used to study historical viral infections and other biological phenomena. The findings could pave the way for more comprehensive studies on extinct species, contributing to conservation efforts and the understanding of biodiversity loss.
What's Next?
Future research will likely focus on expanding this technique to other extinct species, potentially using a combination of RNA, DNA, and protein analysis to gain a more complete picture of ancient life. Scientists may also work on improving methods to prevent contamination and enhance the accuracy of RNA sequencing from old specimens. This could involve developing new protocols for handling and analyzing ancient biological materials. Additionally, the study's findings may encourage museums and research institutions to reassess the preservation and use of their collections for genetic research, potentially leading to new discoveries about extinct species and their ecosystems.
