What's Happening?
Rush University Medical Center has successfully performed the first procedures using the SetPoint System in Chicago, marking a significant advancement in the treatment of rheumatoid arthritis (RA). This FDA-approved neuroimmune modulation therapy is designed
for adults with moderately-to-severely active RA who have not responded adequately to existing treatments. The procedure, led by Dr. Webster Crowley, involves targeted stimulation of the left vagus nerve to regulate immune system activity. This innovative approach offers a new option for patients who cannot tolerate or do not benefit from traditional biological and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). The SetPoint System is currently available at select rheumatology clinics in the Chicago area.
Why It's Important?
The introduction of the SetPoint System in Chicago represents a pivotal development in the management of rheumatoid arthritis, a chronic autoimmune disease affecting millions. This device-based therapy provides an alternative for patients who have exhausted conventional treatment options, potentially improving quality of life and reducing healthcare costs associated with long-term RA management. The system's ability to modulate immune responses through neural pathways could pave the way for broader applications in other autoimmune conditions, such as multiple sclerosis and Crohn's disease. This advancement underscores the growing trend towards personalized and precision medicine in chronic disease management.
What's Next?
Following the successful implementation in Chicago, SetPoint Medical plans to expand access to the SetPoint System across more clinics and potentially explore its application in other autoimmune diseases. Continued collaboration with academic medical centers and rheumatologists will be crucial in evaluating the long-term efficacy and safety of this therapy. As more data becomes available, it could influence treatment guidelines and insurance coverage decisions, impacting how RA and similar conditions are managed nationwide.













