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Ginseng-Derived Lacticaseibacillus rhamnosus Strains Show Promising Probiotic Potential

WHAT'S THE STORY?

What's Happening?

Research has identified Lacticaseibacillus rhamnosus strains derived from ginseng sprouts as having significant probiotic potential, including hypocholesterolemic, antioxidant, and antibacterial activities. The study involved isolating LAB from ginseng sprouts grown under controlled conditions and evaluating their viability against gastrointestinal stressors, bile tolerance, and acid tolerance. The strains demonstrated strong antibacterial activity against pathogenic bacteria such as Escherichia coli and Staphylococcus aureus. Additionally, the strains exhibited antioxidant activity through DPPH and ORAC assays, indicating their potential to combat oxidative stress.
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Why It's Important?

The discovery of these probiotic strains is crucial for the development of alternative treatments for cardiovascular diseases, which are a major health concern in the U.S. The hypocholesterolemic properties of these strains could offer a natural and cost-effective solution to managing cholesterol levels, reducing reliance on pharmaceutical drugs that often come with side effects and high costs. Furthermore, the antioxidant and antibacterial activities of these strains could enhance overall health by reducing oxidative stress and preventing infections, contributing to improved public health outcomes.

What's Next?

Further research will focus on the clinical application of these probiotic strains, including human trials to assess their efficacy and safety. The development of probiotic supplements or functional foods incorporating these strains could be explored, offering consumers new options for managing cholesterol and enhancing health. Additionally, studies will aim to understand the mechanisms behind the probiotic effects, potentially leading to the discovery of more beneficial strains and applications.

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