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DNA Test Identifies Children at Higher Risk of Adult Obesity

WHAT'S THE STORY?

What's Happening?

A new genetic test has been developed to predict the risk of severe obesity in adulthood from early childhood. The test uses a polygenic risk score (PGS) to assess genetic risk variants, allowing for early intervention strategies. The study, involving over 600 scientists and 23andMe, Inc., found that the PGS is twice as effective as previous tests in predicting obesity risk. However, the test is more accurate for individuals with European ancestry compared to those with African ancestry.
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Why It's Important?

This development in genetic testing could revolutionize obesity prevention by enabling early lifestyle interventions for at-risk children. With obesity rates projected to rise globally, such predictive tools are crucial for public health strategies. The test's limitations highlight the need for more inclusive research to ensure its effectiveness across diverse populations. The findings could influence healthcare policies and resource allocation for obesity prevention programs.

What's Next?

Further research is needed to improve the test's accuracy across different ancestries. Healthcare providers may begin integrating genetic testing into routine pediatric assessments to identify children at risk of obesity. Policymakers and public health officials could use these insights to design targeted intervention programs, potentially reducing the long-term health and economic impacts of obesity.

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