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Biogen and Eisai's Leqembi Shows Long-Term Efficacy in Slowing Alzheimer's Progression

WHAT'S THE STORY?

What's Happening?

Biogen and Eisai have presented new data on their anti-amyloid antibody, Leqembi, at the Alzheimer’s Association International Conference. The data, from the Clarity AD study, indicates that Leqembi can slow the progression of Alzheimer’s disease over four years of treatment. Patients treated with Leqembi showed improved cognitive scores compared to expected declines. The study also highlighted that 69% of patients in a tau protein substudy showed no decline or improvement in clinical scores. Despite initial market challenges, Leqembi's sales are increasing, with a reported 30% growth in the third quarter of 2024.
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Why It's Important?

Leqembi's demonstrated efficacy in slowing Alzheimer's progression is significant for patients and the healthcare industry. As the first fully approved anti-amyloid antibody therapy, it offers a new treatment option for early-stage Alzheimer's patients. The increasing sales and positive clinical data may enhance its market position and encourage broader adoption. This development could influence future research and treatment strategies for neurodegenerative diseases, potentially improving patient outcomes and quality of life.

What's Next?

Biogen and Eisai are likely to focus on expanding the prescriber base and promoting the clinical benefits of Leqembi. As sales continue to grow, the companies may invest in further research to solidify Leqembi's efficacy and safety profile. The healthcare community will be watching for additional data and potential regulatory updates that could impact treatment guidelines.

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